According to the American Cancer Society, approximately 1 in 8 men will receive a prostate cancer diagnosis in their lifetime, making it the second leading cause of cancer death after lung cancer. However, a prostate cancer diagnosis is not necessarily a death sentence, as the death rate for this cancer has decreased by about half between 1993 and 2013. In fact, 3.3 million American men who have been diagnosed with prostate cancer are still alive. The National Cancer Institute predicts a 97.5% survival rate after diagnosis, showing that progress is being made in treating this disease.
Researchers at the University of Michigan have made a significant breakthrough in understanding the development of prostate cancer. In a study published in Nature Genetics, they identified the NSD2 protein as a key factor in the development of prostate cancer when it binds with the androgen receptor. Androgens are hormones responsible for male reproductive system growth and development, with testosterone being a prominent example. The androgen receptor is a protein that binds to androgens and regulates genes involved in male sexual development.
The researchers used a CRISPR screening method to study the relationship between NSD2 and the androgen receptor. They found that NSD2 also plays a role in hematologic cancers and is an oncogene in multiple myeloma and childhood acute lymphoblastic leukemia. By targeting NSD2 in further experiments, they hope to confirm the effectiveness of their findings and develop new treatment options for prostate cancer.
Contrary to previous beliefs, choline intake does not cause prostate cancer. A study published in 2012 suggested a link between increased choline intake and an increased risk of lethal prostate cancer. However, the study was observational and did not establish a direct cause-and-effect relationship. Other factors in the diet, such as phytonutrients and fiber, were not considered, and the accuracy of the dietary information collected over 22 years was questionable. Therefore, choline intake alone cannot be blamed for prostate cancer risk. Determining whether the risk of prostate cancer increases in a linear fashion with choline intake or if there is a threshold effect is essential for dietary recommendations. A study examining post-diagnostic choline intake and its correlation with lethal prostate cancer in men initially diagnosed with nonmetastatic disease did not find a statistically significant connection.
Choline is known to be beneficial for overall health, with studies showing that increasing choline intake can lead to decreased risks of heart disease, cancer, and nonalcoholic fatty liver disease. Grass-fed meat, milk, and pastured eggs are among the best dietary sources of choline.
I believe that many major diseases, including cancer, heart disease, and obesity, are linked to poor mitochondrial health. Toxins such as excess linoleic acid intake, endocrine-disrupting chemicals, and excessive electromagnetic field exposure can damage mitochondrial function and lead to health issues. Addressing these factors can help repair mitochondrial function and improve cellular energy production, which is crucial for preventing chronic diseases like cancer.
In addition to addressing mitochondrial function, taking aspirin may also be beneficial for cancer prevention. Research has shown that a combination of B vitamins and aspirin can help regress tumors. Opting for immediate-release formulations of aspirin without unnecessary additives is recommended for optimal health benefits.
By addressing factors that affect mitochondrial function and considering the use of aspirin, individuals can take proactive steps towards preventing cancer and improving overall health. Bajas dosis (75 a 300 mg/día) han demostrado ser tan efectivas como dosis más altas en la reducción de la mortalidad relacionada con el cáncer colorrectal, lo que significa que no es necesario tomar grandes cantidades para obtener los beneficios.
No obstante, la clave parece ser la consistencia y el uso a largo plazo. Estudios indican que los beneficios de la aspirina aumentan con la duración, con reducciones significativas en el riesgo de cáncer observadas después de cinco a 7.5 años de uso consistente.
Personalmente tomo 111 mg diarios usando el polvo de aspirina USP de Health Natura, que cuesta menos de $20. Este polvo de aspirina USP 99% puro me atrae debido a sus efectos prometabólicos, antilipolíticos, antiinflamatorios, anticortisol y antiestrógeno. Su perfil de seguridad también está bien establecido.